Seminar | March 22 | 3-4 p.m. | 125 Li Ka Shing
Dr. Alejandro Chavez, University of California, San Diego
Center for Computational Biology
Abstract:
During this presentation I will share three technologies designed to speed the rate at which small molecules are screened, protein function interrogated, and designer proteins are generated and tested. During the presentation each method will be described along with an example use case to illustrate the utility of the approach. Application areas to be discussed involve the identification of small molecule protease inhibitors, examining the dynamic behavior of stress granule associated proteins, and the generation of improved CRISPR-activators.
Biography:
Dr. Chavez completed his Bachelor of Arts at Northwestern University,
M.D./Ph.D. at the University of Pennsylvania, residency in Clinical
Pathology at Massachusetts General Hospital, and postdoctoral
training at the Wyss Institute at Harvard. He was an Assistant
Professor in the Department of Pathology at Columbia University,
before taking a position as an Associate Professor in the Department
of Pediatrics at the University of California San Diego. His laboratory
focuses on the development of high-throughput genome engineering
and screening technologies to speed the rate of discovery, with a
particular interest in applying these tools to the fields of
neurodegeneration and infectious disease. Dr. Chavez is the recipient
of various awards including the NIH New Innovator Award, Career
Award for Medical Scientists from the Burroughs Wellcome Fund and
grants from DARPA, DoD, CZI, and the Silicon Valley Community
Foundation.
ccbadmin@berkeley.edu, 510-664-5456
Center for Computational Biology, ccbadmin@berkeley.edu, 510-664-5456